How to Start Biohacking

Daniel Domaradzki / 07 Sep ’25

Silhouette of a man practicing a biohacking meditation

Starting to biohack is the process of becoming an active participant in your own health and well-being. It means moving from passively accepting your biological state to actively and intentionally improving it. The good news is that you don’t need expensive gadgets or a degree in biology to begin. The most effective biohacks are often simple, foundational lifestyle changes that you can start today.

The First Step: Define Your Goal and Baseline

Before you make any changes, the most important step is to know what you are trying to improve. A vague goal like “be healthier” is not useful. A specific goal is actionable. Choose one clear objective:

  • “I want to have more energy in the afternoons.”
  • “I want to improve the quality of my deep sleep.”
  • “I want to reduce my baseline level of stress.”

Once you have a goal, establish a baseline. For one week, track the relevant metric without making any changes. This could involve using a sleep tracking app, rating your energy level on a scale of 1-10 each afternoon, or simply journaling about your stress levels. This baseline is your control data.

Note: While subjective journaling is a starting point, integrating wearable technology or establishing baseline biomarkers through standard blood panels provides quantifiable, objective data.

How to “Do” Biohacking: The N=1 Experiment

Biohacking is a process of methodical self-experimentation where you are the single subject of your own study (an “n=1” experiment). The process is simple:

  1. Introduce One Variable: Make only one specific change at a time. If you change your diet, your supplement routine, and your sleep schedule all at once, you will have no idea which variable caused the effect.
  2. Track the Output: For a set period (e.g., two weeks), continue to track the same metric you measured for your baseline.
  3. Analyze and Conclude: Compare the data from your intervention period to your baseline data. Did your afternoon energy levels improve? Did your deep sleep increase? If the change was positive, you can adopt it. If it was negative or had no effect, you can discard it and return to your baseline before testing a new variable.
  4. Be Critical: Remain acutely aware of the placebo effect; subjective improvements can stem purely from the psychological expectation of an intervention working, highlighting the need for rigorous, prolonged tracking.

Simple Biohacks to Start With Today

Begin with low-risk, high-impact practices that form the foundation of good health.

Optimize Your Sleep

Sleep is the most powerful performance and health enhancer available. Sleep optimization is a foundational biohack.

Action: For one week, eliminate all blue light from screens (phones, TVs, computers) for at least one hour before bed. Make your bedroom as dark and cool as possible. Go to bed and wake up at the same time every day. Track your sleep quality and next-day energy levels.

Execute an Elimination Diet

Many feelings of fatigue and brain fog are driven by subclinical food sensitivities. A structured elimination diet is a highly effective biohack for isolating triggers.

Action: For a minimum of 21 days, completely remove common allergens from your nutritional intake. Track systemic inflammation indicators such as joint pain, gastrointestinal distress, and cognitive clarity. Reintroduce these foods one at a time, separated by 72 hours, and observe the physiological response to identify specific intolerances.

Use Cold Exposure

Cold exposure is a form of hormesis—a brief, manageable stress that makes your body stronger. It can reduce inflammation and increase alertness.

Action: End your regular warm shower with 30-60 seconds of pure cold water. Focus on controlling your breath and staying calm. Do this daily and note its effect on your mood and energy immediately afterward.

Get Morning Sunlight

Exposing your eyes and skin to direct sunlight shortly after waking is a primary signal for setting your body’s circadian rhythm (your internal 24-hour clock).

Action: Within 30 minutes of waking, go outside for 5-10 minutes without sunglasses. The morning light hitting your retinas helps to regulate the hormones that control your sleep-wake cycle, leading to more energy during the day and better sleep at night.

Meditate and Practice Breathwork

These practices are direct tools for regulating your autonomic nervous system. They positively contribute to your baseline calm and also improve your self-awareness as well as self-control.

Action: Practice five minutes of box breathing (inhale, hold, exhale, and hold again for a roughly even amount of seconds) each morning. This simple breathwork exercise can lower your baseline stress level and improve your focus throughout the day. You may also introduce mindfulness meditations to your daily routine.

Optimize Cellular Respiration

Cardiovascular efficiency dictates your body’s ability to produce ATP (cellular energy). Integrating targeted metabolic conditioning is non-negotiable for longevity.

Action: Incorporate 90 minutes (or more) of zone 2 (at least) training per week. Zone 2 entails maintaining a steady heart rate where you can comfortably hold a conversation, optimizing mitochondrial density and improving your Heart Rate Variability (HRV). If you can manage it, signing up for more intense workout classes (e.g., martial arts, dance, etc.) could be an even better choice.

Note: Manage your fatigue and recovery levels if you decide to take part in more vigorous activities to prevent overtraining.

Prioritize Structural Integrity

Musculoskeletal health is frequently overshadowed by dietary interventions, yet fundamental biomechanics govern your daily energy expenditure and physical resilience.

Action: Join your local gym and exercise at least twice a week, focusing on joint mobilization and resistance training. Enhancing your mechanical efficiency prevents chronic pain and mitigates the physiological stress associated with poor posture and muscular imbalances.

Note: Resistance training damages muscle tissue. Ensure you can recover from your gym sessions before taking part in other intense physical activities. If you do any sports, train at lower RPE and frequency to ensure proper recovery and void injuries.

Is Biohacking Legit

Yes, the principles of biohacking are legitimate. The core methodology—methodical self-experimentation—is a form of the scientific method. Many of the most common practices, such as meditation, dietary modification, and sleep hygiene, are supported by a vast body of scientific evidence. The legitimacy of any specific biohack depends on the quality of the evidence supporting it.

The Risks of Biohacking

The safety of biohacking exists on a spectrum. It is crucial to perform a risk assessment before trying any new practice.

  • Low-Risk: The foundational biohacks listed above are extremely safe and based on healthy lifestyle principles.
  • Moderate-Risk: This includes taking unregulated supplements or nootropics, where the long-term effects may not be well-studied. This requires significant personal research.
  • High-Risk: This is the realm of “grinder” biohacking, which involves things like implanting microchips or engaging in DIY gene editing. These practices are unregulated, carry a high risk of infection and long-term harm, and should not be undertaken without extreme caution and expertise.

To start your journey, stick to the low-risk, foundational practices. Master your sleep, your diet, and your breath before exploring more complex interventions.